Search Pubmed
48. Wall SW, Sanchez L, Tuttle KS, Pearson SJ, Soma S, Wyatt GL, Carter HN, Jenschke RM, Tan L, Martinez SA, Lorenzi PL, Gohil VM, Rijnkels M, Porter WW. Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer. Exp Mol
Med. doi: 10.1038/s12276-023-00996-0. Epub ahead of print. PMID: 37121978.
47. Zulkifli M, Spelbring AM, Zhang Y, Soma S, Chen S, Li L, Le T, Shanbhag V, Petris MJ, Chen T, Ralle M, Barondeau DP, Gohil VM (2023) FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery. Proc Natl Acad Sci U S A. 120(10):e2216722120.
46. Garza NM, Swaminathan AB, Maremanda KP, Zulkifli M, Gohil VM. Mitochondrial copper in human genetic disorders. Trends Endocrinol Metab. doi: 10.1016/j.tem.2022.11.001. Epub ahead of print. PMID: 36435678.
45. Jett KA, Baker ZN, Hossain A, Boulet A, Cobine PA, Ghosh S, Ng P, Yilmaz O, Barreto K, DeCoteau J, Mochoruk K, Ioannou GN, Savard C, Yuan S, Abdalla OH, Lowden C, Kim BE, Cheng HM, Battersby BJ, Gohil VM, Leary SC. (2022) Mitochondrial dysfunction reactivates α-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models. J. Clin. Invest. doi: 10.1172/JCI154684. Online ahead of print. PMID: 36247001.
44. Wasilewski M, Gohil VM, Khalimonchuk O. (2022) Editorial: Function and formation of mitochondrial metalloproteome. Frontiers in Cell and Developmental Biology. 10:1020441.
43. Garza NM, Zulkifli M, Gohil V.M. (2022) Elesclomol elevates cellular and mitochondrial iron levels by delivering copper to the iron import machinery. J. Biol. Chem. doi: 10.1016/j.jbc.2022.102139. Online ahead of print. PMID: 35714767.
42. Swaminathan AB, Soma S, Vicary AC, Zulkifli M, Kaur H, Gohil V.M. (2022) A yeast suppressor screen links Coa4 to the mitochondrial copper delivery pathway for cytochrome c oxidase. Genetics. doi: 10.1093/genetics/iyac090. Online ahead of print. PMID: 35666203.
41. Swaminathan AB, Gohil V.M. (2022) The Role of COA6 in the Mitochondrial Copper Delivery Pathway to Cytochrome c Oxidase. Biomolecules. 12(1):125.
40. Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, Ralle M, Schilsky ML, Tonks NK, Vahdat LT, Van Aelst L, Xi D, Yuan P, Brady DC, Chang CJ. (2022) Connecting copper and cancer: from transition metal signalling to metalloplasia. Nat Rev Cancer. 22: 102–113
39. Ghosh S, Zulkifli M, Joshi A, Venkatesan M, Cristel A, Vishnu N, Madesh M, Gohil V.M. (2022) MCU-complex-mediated mitochondrial calcium signaling is impaired in Barth syndrome. Hum Mol Genet. 31(3):376-385.
38. Iadarola, D.M., Joshi, A., Caldwell, C.B., Gohil, V.M. (2021) Choline restores respiration in Psd1-deficient yeast by replenishing mitochondrial phosphatidylethanolamine. J. Biol. Chem. 296:100539.
37. Garza, N.M., Griffin, A.T., Zulkifli, M., Qiu, C., Kaplan, C.D., Gohil, V.M. (2021) A genome wide copper-sensitized screen identifies novel regulators of mitochondrial cytochrome c oxidase activity. J. Biol. Chem. 296:100485.
36. Alevriadou, B.R., Patel, A., Noble, M., Ghosh, S., Gohil, V.M., Stathopulos, P.B., Madesh, M. (2021) Molecular Nature and Physiological Role of the Mitochondrial Calcium Uniporter Channel. Am J Physiol Cell Physiol. 320(4):C465-C482.
35. Gohil, V.M. (2021) Repurposing elesclomol, an investigational drug for the treatment of copper metabolism disorders. Expert Opin Investig Drugs. 30(1): 1-4.
34. Zulkifli, M., Neff, J.K., Timbalia, S.A., Garza, N.M., Chen, Y., Watrous, J.D., Murgia, M., Trivedi, P.P., Anderson, S.K., Tomar, D., Nilsson,
R., Madesh, M., Jain, M., Gohil, V.M. (2020) Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism. Nat Commun. 11(1):4866.
33. Ghosh, S., Ball, W.B., Madaris, T.R., Srikantan, S., Madesh, M., Mootha, V.K.*, Gohil, V.M.* (2020) An Essential Role for Cardiolipin in the Stability and Function of the Mitochondrial Calcium Uniporter. Proc Natl Acad Sci U S A. 117(28):16383-16390 *Co-corresponding authors
32. Guthrie, L.M., Soma, S., Yuan, S., Silva, A., Zulkifli, M., Snavely, T.C., Greene, H.F., Nunez, E., Lynch, B., De Ville, C., Shanbhag, V., Lopez, F.R., Acharya, A., Petris, M.J., Kim, B.E., Gohil, V.M.*, Sacchettini, J.C.* (2020) Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice. Science. 368(6491):620-625. *Co-corresponding authors
31. Iadarola, D.M., Ball, W.B., Trivedi, P.P., Fu, G., Nan, B., Gohil, V.M. (2020) Vps39 is required for ethanolamine-stimulated elevation in mitochondrial phosphatidylethanolamine. Biochim Biophys Acta Mol Cell Biol Lipids. 1865(6):158655.
30. Soma, S., Morgada, M.N., Naik, M.T., Boulet, A., Roesler, A.A., Dziuba,N., Ghosh, A., Yu, Q., Lindahl, P.A., Ames, J.B., Leary, S.C., Vila, A.J., Gohil, V.M. (2019) COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase. Cell Reports. 29(12):4114-4126.e5.
29. Ghosh S., Iadarola D.M., Ball W.B., Gohil V.M. (2019) Mitochondrial Dysfunctions in Barth Syndrome. IUBMB Life. 71: 791-801.
28. Soma, S., Latimer, A.J., Chun, H., Vicary, A.C., Timbalia, S.A., Boulet, A., Rahn, J.J., Chan, S.S.L., Leary, S.C., Kim, B.-E., Gitlin, J.D., Gohil, V.M. (2018) Elesclomol restores mitochondrial function in genetic models of copper deficiency. Proc. Natl. Acad. Sci. U.S.A. 115: 8161-6.
27. Ball, W.B., Baker, C.D., Neff, J.K., Apfel, G.L., Lagerborg, K.A., Zun, G., Petrovic, U., Jain, M., Gohil, V.M. (2018) Ethanolamine ameliorates mitochondrial dysfunction in cardiolipin-deficient yeast cells. J. Biol. Chem. 293: 10870-83.
26. Ball, W.B., Neff, J.K., Gohil, V.M. (2017) The role of nonbilayer phospholipids in mitochondrial structure and function. FEBS Lett. 592: 1273-290.
25. Baker, C.D., Ball, W.B., Pryce, E.N., Gohil, V.M. (2016) Specific requirements of non-bilayer phospholipids in mitochondrial respiratory chain function and formation. Mol. Biol. Cell. 27: 2161-171.
24. Tomar, D., Dong, Z., Shanmughapriya, S., Koch, D.A., Thomas, T., Hoffman, N.E., Timbalia, S.A., Goldman, S.J., Breves, S.L., Corbally, D.P., Nemani, N., Fairweather, J.P., Cutri, A.R., Zhang, X., Song, J., Jaña, F., Huang, J., Barrero, C., Rabinowitz, J., Luongo, T., Schumacher, S.M., Rockman, M.E., Dietrich, A., Merali, S., Caplan, J., Stathopulos, P., Ahima, R.S., Cheung, J.Y., Houser, S.R., Koch, W.J., Patel, V., Gohil, V.M., Elrod, J.W., Sudarsan, R., Madesh, M. (2016) MCUR1 Is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics. Cell Reports. 15: 1673–685.
23. Ghosh, A., Pratt, A.T., Soma, S., Theriault, S.G., Griffin, A.T., Trivedi, P.P., Gohil, V.M. (2015) Mitochondrial disease genes COA6, COX6B and SCO2 have overlapping roles in COX2 biogenesis. Hum. Mol. Genet. 25: 660-71.
22. Kishi, S., Campanholle, G., Gohil, V.M., Perocchi, G., Brooks, C.R., Morizane, R., Sabbisetti, V., Ichimura, T., Mootha, V.K., Bonventre, J.V. (2015) Meclizine preconditioning protects the kidney against ichemia-reperfusion injury. EBioMedicine. 9: 1090-101.
21. Ghosh, A., Trivedi, P.P., Timbalia, S.A., Griffin, A.T., Rahn, J.J., Chan, S.S.L., Gohil, V.M. (2014) Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency. Hum. Mol. Genet. 23: 3596-606.
20. Jhurry, N.D., Chakrabarti, M., McCormick, S.P., Gohil, V.M., Lindahl, P.A. (2013) Mössbauer study and modeling of iron import and trafficking in human Jurkat cells. Biochemistry 52: 7926-942.
19. Gohil, V.M.*, Zhu, L., Baker, C.D., Cracan, V., Yaseen, A., Jain, M., Clish, C.B., Brookes, P.S., Bakovic, M., Mootha, V.K.* (2013) Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism. J. Biol. Chem. 288: 5387- 395. *Co-corresponding authors
18. Patil, V.A., Fox, J.L., Gohil, V.M., Winge, D.R., & Greenberg, M.L. (2013) Loss of cardiolipin leads to perturbation of mitochondrial and cellular iron homeostasis. J. Biol. Chem. 288: 1696-705.
17. Gohil, V.M.*, Offner, N., Walker, J.A., Sheth, S.A., Fossale, E., Gusella, J.F., MacDonald, M.E., Neri, C., Mootha, V.K.* (2011) Meclizine is neuroprotective in models of Huntington’s disease. Hum. Mol. Genet. 20: 294-300. *Co-corresponding authors
16. Perocchi, F., Gohil, V.M., Girgis, H.S., Bao, X.R., McCombs, J.E., Palmer, A.E., Mootha, V.K. (2010) MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake. Nature 467: 291-6.
15. Gohil, V.M., Nilsson, R., Belcher-Timme, C.A., Luo, B., Root, D.E., Mootha, V.K. (2010) Mitochondrial and nuclear genomic responses to loss of LRPPRC expression. J. Biol. Chem 285: 13742-7.
14. Gohil, V.M., Sheth, S.A., Nilsson, R., Wojtovich, A.P., Lee, J.H., Perocchi, F., Chen, W., Clish, C.B., Ayata, C., Brookes, P.S., Mootha, V.K. (2010) Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis. Nat. Biotechnol. 28: 249-55.
13. Baughman, J.M., Nilsson, R., Gohil, V.M., Arlow, D.H., Gauhar, Z., Mootha, V.K. (2009). A computational screen for regulators of. oxidative phosphorylation implicates SLIRP in mitochondrial RNA homeostasis. PLoS Genet. 5(8):e1000590
12. Gohil, V.M., Greenberg, M.L. (2009). Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand.
J. Cell Biol. 184(4): 469-472
11. Joshi, A.S., Zhou, J., Gohil, V.M., Chen, S., Greenberg, M.L. (2009) Cellular functions of cardiolipin in yeast. Biochim. Biophys. Acta 1793 (1): 212-218.
10. Gohil, V.M., Thompson, M.N., Greenberg, M.L. (2005) Synthetic lethal interaction between mitochondrial cardiolipin and
phosphatidylethanolamine biosynthetic pathways. J. Biol. Chem. 280(42): 35410-35416.
9. Gohil, V.M., Gvozdenovic-Jeremic, J., Schlame, M., Greenberg, M.L. (2005) Binding of 10-N-nonyl acridine orange to cardiolipin deficient yeast cells: implications for assay of cardiolipin. Anal. Biochem. 343(2): 350-352.
8. Vaden, D.L., Gohil, V.M., Gu, Z., Greenberg, M.L. (2005) Separation and quantification of yeast phospholipids. Anal. Biochem. 338 (1): 162-164.
7. Gohil, V.M., Hayes, P., Matsuyama, S., Schagger, H., Schlame, M., Greenberg, M.L. (2004) Cardiolipin biosynthesis and
mitochondrial respiratory chain function are interdependent. J. Biol. Chem. 279(41): 42612-42618.
6. Zhong, Q., Gohil, V.M., Ma, L., Greenberg, M.L. (2004) Deletion of CRD1 results in temperature sensitivity, respiratory defects, and mitochondrial DNA instability independent of pet56. J. Biol. Chem. 279(31): 32294-32300.
5. Pfeiffer, K., Gohil, V., Stuart, R.A., Hunte, C., Brandt, U., Greenberg, M.L., and Schägger, H. (2003) Cardiolipin stabilizes respiratory chain supercomplexes. J. Biol. Chem. 278(52): 52873-52880.
4. Gupta, S., Laxmipriya, Gohil, V.M. (2002) Simultaneous exposure of lead and cadmium on granulosa cells, progesterone and luteinizing hormone in pro-estrous rats. Adv. Pharmacol. Toxicol. 3(2): 23-30.
3. Gu, Z., Gohil, V.M., Zhong, Q., Schlame, M., Greenberg, M.L. (2002) The biosynthesis and remodeling of cardiolipin. LIPIDS: Glycerolipid Metabolizing Enzymes: 67-84, Haldar, D., ed., Kerala: Research Signpost Press.
2. Prasad, N.G., Shakarad, M., Gohil, V.M., Sheeba, V., Rajamani, M., Joshi, A. (2000) Evolution of reduced pre-adult viability and larval growth rate in laboratory populations of Drosophila melanogaster selected for shorter development time. Genet. Res. 76 (3): 249-259.
1. Gohil, V.M., Joshi, A. (1998) Modelling the evolution of rates of ageing. Resonance. 3(8): 67-72.
48. Wall SW, Sanchez L, Tuttle KS, Pearson SJ, Soma S, Wyatt GL, Carter HN, Jenschke RM, Tan L, Martinez SA, Lorenzi PL, Gohil VM, Rijnkels M, Porter WW. Noncanonical role of singleminded-2s in mitochondrial respiratory chain formation in breast cancer. Exp Mol
Med. doi: 10.1038/s12276-023-00996-0. Epub ahead of print. PMID: 37121978.
47. Zulkifli M, Spelbring AM, Zhang Y, Soma S, Chen S, Li L, Le T, Shanbhag V, Petris MJ, Chen T, Ralle M, Barondeau DP, Gohil VM (2023) FDX1-dependent and independent mechanisms of elesclomol-mediated intracellular copper delivery. Proc Natl Acad Sci U S A. 120(10):e2216722120.
46. Garza NM, Swaminathan AB, Maremanda KP, Zulkifli M, Gohil VM. Mitochondrial copper in human genetic disorders. Trends Endocrinol Metab. doi: 10.1016/j.tem.2022.11.001. Epub ahead of print. PMID: 36435678.
45. Jett KA, Baker ZN, Hossain A, Boulet A, Cobine PA, Ghosh S, Ng P, Yilmaz O, Barreto K, DeCoteau J, Mochoruk K, Ioannou GN, Savard C, Yuan S, Abdalla OH, Lowden C, Kim BE, Cheng HM, Battersby BJ, Gohil VM, Leary SC. (2022) Mitochondrial dysfunction reactivates α-fetoprotein expression that drives copper-dependent immunosuppression in mitochondrial disease models. J. Clin. Invest. doi: 10.1172/JCI154684. Online ahead of print. PMID: 36247001.
44. Wasilewski M, Gohil VM, Khalimonchuk O. (2022) Editorial: Function and formation of mitochondrial metalloproteome. Frontiers in Cell and Developmental Biology. 10:1020441.
43. Garza NM, Zulkifli M, Gohil V.M. (2022) Elesclomol elevates cellular and mitochondrial iron levels by delivering copper to the iron import machinery. J. Biol. Chem. doi: 10.1016/j.jbc.2022.102139. Online ahead of print. PMID: 35714767.
42. Swaminathan AB, Soma S, Vicary AC, Zulkifli M, Kaur H, Gohil V.M. (2022) A yeast suppressor screen links Coa4 to the mitochondrial copper delivery pathway for cytochrome c oxidase. Genetics. doi: 10.1093/genetics/iyac090. Online ahead of print. PMID: 35666203.
41. Swaminathan AB, Gohil V.M. (2022) The Role of COA6 in the Mitochondrial Copper Delivery Pathway to Cytochrome c Oxidase. Biomolecules. 12(1):125.
40. Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, Ralle M, Schilsky ML, Tonks NK, Vahdat LT, Van Aelst L, Xi D, Yuan P, Brady DC, Chang CJ. (2022) Connecting copper and cancer: from transition metal signalling to metalloplasia. Nat Rev Cancer. 22: 102–113
39. Ghosh S, Zulkifli M, Joshi A, Venkatesan M, Cristel A, Vishnu N, Madesh M, Gohil V.M. (2022) MCU-complex-mediated mitochondrial calcium signaling is impaired in Barth syndrome. Hum Mol Genet. 31(3):376-385.
38. Iadarola, D.M., Joshi, A., Caldwell, C.B., Gohil, V.M. (2021) Choline restores respiration in Psd1-deficient yeast by replenishing mitochondrial phosphatidylethanolamine. J. Biol. Chem. 296:100539.
37. Garza, N.M., Griffin, A.T., Zulkifli, M., Qiu, C., Kaplan, C.D., Gohil, V.M. (2021) A genome wide copper-sensitized screen identifies novel regulators of mitochondrial cytochrome c oxidase activity. J. Biol. Chem. 296:100485.
36. Alevriadou, B.R., Patel, A., Noble, M., Ghosh, S., Gohil, V.M., Stathopulos, P.B., Madesh, M. (2021) Molecular Nature and Physiological Role of the Mitochondrial Calcium Uniporter Channel. Am J Physiol Cell Physiol. 320(4):C465-C482.
35. Gohil, V.M. (2021) Repurposing elesclomol, an investigational drug for the treatment of copper metabolism disorders. Expert Opin Investig Drugs. 30(1): 1-4.
34. Zulkifli, M., Neff, J.K., Timbalia, S.A., Garza, N.M., Chen, Y., Watrous, J.D., Murgia, M., Trivedi, P.P., Anderson, S.K., Tomar, D., Nilsson,
R., Madesh, M., Jain, M., Gohil, V.M. (2020) Yeast homologs of human MCUR1 regulate mitochondrial proline metabolism. Nat Commun. 11(1):4866.
33. Ghosh, S., Ball, W.B., Madaris, T.R., Srikantan, S., Madesh, M., Mootha, V.K.*, Gohil, V.M.* (2020) An Essential Role for Cardiolipin in the Stability and Function of the Mitochondrial Calcium Uniporter. Proc Natl Acad Sci U S A. 117(28):16383-16390 *Co-corresponding authors
32. Guthrie, L.M., Soma, S., Yuan, S., Silva, A., Zulkifli, M., Snavely, T.C., Greene, H.F., Nunez, E., Lynch, B., De Ville, C., Shanbhag, V., Lopez, F.R., Acharya, A., Petris, M.J., Kim, B.E., Gohil, V.M.*, Sacchettini, J.C.* (2020) Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice. Science. 368(6491):620-625. *Co-corresponding authors
31. Iadarola, D.M., Ball, W.B., Trivedi, P.P., Fu, G., Nan, B., Gohil, V.M. (2020) Vps39 is required for ethanolamine-stimulated elevation in mitochondrial phosphatidylethanolamine. Biochim Biophys Acta Mol Cell Biol Lipids. 1865(6):158655.
30. Soma, S., Morgada, M.N., Naik, M.T., Boulet, A., Roesler, A.A., Dziuba,N., Ghosh, A., Yu, Q., Lindahl, P.A., Ames, J.B., Leary, S.C., Vila, A.J., Gohil, V.M. (2019) COA6 Is Structurally Tuned to Function as a Thiol-Disulfide Oxidoreductase in Copper Delivery to Mitochondrial Cytochrome c Oxidase. Cell Reports. 29(12):4114-4126.e5.
29. Ghosh S., Iadarola D.M., Ball W.B., Gohil V.M. (2019) Mitochondrial Dysfunctions in Barth Syndrome. IUBMB Life. 71: 791-801.
28. Soma, S., Latimer, A.J., Chun, H., Vicary, A.C., Timbalia, S.A., Boulet, A., Rahn, J.J., Chan, S.S.L., Leary, S.C., Kim, B.-E., Gitlin, J.D., Gohil, V.M. (2018) Elesclomol restores mitochondrial function in genetic models of copper deficiency. Proc. Natl. Acad. Sci. U.S.A. 115: 8161-6.
27. Ball, W.B., Baker, C.D., Neff, J.K., Apfel, G.L., Lagerborg, K.A., Zun, G., Petrovic, U., Jain, M., Gohil, V.M. (2018) Ethanolamine ameliorates mitochondrial dysfunction in cardiolipin-deficient yeast cells. J. Biol. Chem. 293: 10870-83.
26. Ball, W.B., Neff, J.K., Gohil, V.M. (2017) The role of nonbilayer phospholipids in mitochondrial structure and function. FEBS Lett. 592: 1273-290.
25. Baker, C.D., Ball, W.B., Pryce, E.N., Gohil, V.M. (2016) Specific requirements of non-bilayer phospholipids in mitochondrial respiratory chain function and formation. Mol. Biol. Cell. 27: 2161-171.
24. Tomar, D., Dong, Z., Shanmughapriya, S., Koch, D.A., Thomas, T., Hoffman, N.E., Timbalia, S.A., Goldman, S.J., Breves, S.L., Corbally, D.P., Nemani, N., Fairweather, J.P., Cutri, A.R., Zhang, X., Song, J., Jaña, F., Huang, J., Barrero, C., Rabinowitz, J., Luongo, T., Schumacher, S.M., Rockman, M.E., Dietrich, A., Merali, S., Caplan, J., Stathopulos, P., Ahima, R.S., Cheung, J.Y., Houser, S.R., Koch, W.J., Patel, V., Gohil, V.M., Elrod, J.W., Sudarsan, R., Madesh, M. (2016) MCUR1 Is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics. Cell Reports. 15: 1673–685.
23. Ghosh, A., Pratt, A.T., Soma, S., Theriault, S.G., Griffin, A.T., Trivedi, P.P., Gohil, V.M. (2015) Mitochondrial disease genes COA6, COX6B and SCO2 have overlapping roles in COX2 biogenesis. Hum. Mol. Genet. 25: 660-71.
22. Kishi, S., Campanholle, G., Gohil, V.M., Perocchi, G., Brooks, C.R., Morizane, R., Sabbisetti, V., Ichimura, T., Mootha, V.K., Bonventre, J.V. (2015) Meclizine preconditioning protects the kidney against ichemia-reperfusion injury. EBioMedicine. 9: 1090-101.
21. Ghosh, A., Trivedi, P.P., Timbalia, S.A., Griffin, A.T., Rahn, J.J., Chan, S.S.L., Gohil, V.M. (2014) Copper supplementation restores cytochrome c oxidase assembly defect in a mitochondrial disease model of COA6 deficiency. Hum. Mol. Genet. 23: 3596-606.
20. Jhurry, N.D., Chakrabarti, M., McCormick, S.P., Gohil, V.M., Lindahl, P.A. (2013) Mössbauer study and modeling of iron import and trafficking in human Jurkat cells. Biochemistry 52: 7926-942.
19. Gohil, V.M.*, Zhu, L., Baker, C.D., Cracan, V., Yaseen, A., Jain, M., Clish, C.B., Brookes, P.S., Bakovic, M., Mootha, V.K.* (2013) Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism. J. Biol. Chem. 288: 5387- 395. *Co-corresponding authors
18. Patil, V.A., Fox, J.L., Gohil, V.M., Winge, D.R., & Greenberg, M.L. (2013) Loss of cardiolipin leads to perturbation of mitochondrial and cellular iron homeostasis. J. Biol. Chem. 288: 1696-705.
17. Gohil, V.M.*, Offner, N., Walker, J.A., Sheth, S.A., Fossale, E., Gusella, J.F., MacDonald, M.E., Neri, C., Mootha, V.K.* (2011) Meclizine is neuroprotective in models of Huntington’s disease. Hum. Mol. Genet. 20: 294-300. *Co-corresponding authors
16. Perocchi, F., Gohil, V.M., Girgis, H.S., Bao, X.R., McCombs, J.E., Palmer, A.E., Mootha, V.K. (2010) MICU1 encodes a mitochondrial EF hand protein required for Ca(2+) uptake. Nature 467: 291-6.
15. Gohil, V.M., Nilsson, R., Belcher-Timme, C.A., Luo, B., Root, D.E., Mootha, V.K. (2010) Mitochondrial and nuclear genomic responses to loss of LRPPRC expression. J. Biol. Chem 285: 13742-7.
14. Gohil, V.M., Sheth, S.A., Nilsson, R., Wojtovich, A.P., Lee, J.H., Perocchi, F., Chen, W., Clish, C.B., Ayata, C., Brookes, P.S., Mootha, V.K. (2010) Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis. Nat. Biotechnol. 28: 249-55.
13. Baughman, J.M., Nilsson, R., Gohil, V.M., Arlow, D.H., Gauhar, Z., Mootha, V.K. (2009). A computational screen for regulators of. oxidative phosphorylation implicates SLIRP in mitochondrial RNA homeostasis. PLoS Genet. 5(8):e1000590
12. Gohil, V.M., Greenberg, M.L. (2009). Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand.
J. Cell Biol. 184(4): 469-472
11. Joshi, A.S., Zhou, J., Gohil, V.M., Chen, S., Greenberg, M.L. (2009) Cellular functions of cardiolipin in yeast. Biochim. Biophys. Acta 1793 (1): 212-218.
10. Gohil, V.M., Thompson, M.N., Greenberg, M.L. (2005) Synthetic lethal interaction between mitochondrial cardiolipin and
phosphatidylethanolamine biosynthetic pathways. J. Biol. Chem. 280(42): 35410-35416.
9. Gohil, V.M., Gvozdenovic-Jeremic, J., Schlame, M., Greenberg, M.L. (2005) Binding of 10-N-nonyl acridine orange to cardiolipin deficient yeast cells: implications for assay of cardiolipin. Anal. Biochem. 343(2): 350-352.
8. Vaden, D.L., Gohil, V.M., Gu, Z., Greenberg, M.L. (2005) Separation and quantification of yeast phospholipids. Anal. Biochem. 338 (1): 162-164.
7. Gohil, V.M., Hayes, P., Matsuyama, S., Schagger, H., Schlame, M., Greenberg, M.L. (2004) Cardiolipin biosynthesis and
mitochondrial respiratory chain function are interdependent. J. Biol. Chem. 279(41): 42612-42618.
6. Zhong, Q., Gohil, V.M., Ma, L., Greenberg, M.L. (2004) Deletion of CRD1 results in temperature sensitivity, respiratory defects, and mitochondrial DNA instability independent of pet56. J. Biol. Chem. 279(31): 32294-32300.
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